prof. MUDr. Pavel Kraml, Ph.D.

Dept. of Internal Medicine, Third Faculty of Medicine, Charles University Prague and University Hospital Královské Vinohrady, Prague

Center for research of diabetes, metabolism and nutrition

Center for diagnosis and treatment of hyperlipoproteinemia

https://www.lf3.cuni.cz/3LF-654.html


Topic title

New risk factors of atherosclerosis associated cardiovascular diseases


Description of scientific activity

The scientific activity is focused on the non-traditional risk factors of atherosclerosis – iron, inflammation, oncological therapy.


Selected publications

Kraml PJ, Klein RL, Huang Y, Nareika A, Lopes-Virella MF: Iron Loading Enhances LDL Uptake via MSR-I Scavenger Receptor in THP-I Macrophages. Metabolism 2005; 54:453-459 doi: 10.1016/j.metabol.2004.10.012.


Šiklová M, Koc M, Rossmeislová L, Kraml P: Serum oxLDL-β2GPI complex reflects metabolit syndrome and inflammation in adipose tissue in obese. Int J Obes (Lond) 2017; doi 201710.1038/ijo.2017.260


Riško P, Pláteník J, Buchal R, Potočková J, Kraml PJ: Long-term donors versus non-donor men: Iron metabolism and the atherosclerosis process. Atherosclerosis 2018; 272: 14-20. doi: 10.1016/j.atherosclerosis.2018.03.009. Epub 2018 Mar 3. PMID: 29544084.


Cepelova M, Kruseova J, Luks A, Capek V, Cepela P, Potockova J, Kraml P. Accelerated atherosclerosis, hyperlipoproteinemia and insulin resistance in long-term survivors of Hodgkin lymphoma during childhood and adolescence. Neoplasma. 2019 Jul 12;66(6):978-987. doi: 10.4149/neo_2019_190115N45.


Selected or ongoing grants/clinical studies

2012 – 2015 IGA MZ ČR NT13671-4/2012: Reactive iron in monocytes and its role in the process of atherogenesis

2015 – 2018 AZV MZČR 15-30494A: Incidence of hyperlipoproteinemia in long-term survivors of Hodgkin lymphoma during childhood and adolescence.

2014 – 2019 Research program PRVOUK 031: Ferritin as a predictor of the cardiovascular and oncological diseases


PhD Students

Number of PhD students currently studying : 1

Number of defended students with year of defence: 2 (2011, 2019)



Last change: October 3, 2022 10:05 
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