Pain in experimental models: mechanisms and evaluation
Mentor (Advisor):
Šimon Vaculín, AssocProf., MVD, PhD
Department:
Department of Normal, Pathological and Clinical Physiology
Contact information:
Project Narrative:
Animal models are used inneuropathicpain research.Most frequently used method of pain evaluation is detection of evoked hyperalgesia/allodynia. However, it is still not clear how to evaluate spontaneous pain and which parameters beside pain might play a significant role. Therefore the PhD research will be focused on pain evaluation and treatment in laboratory animals. The student will gain skills in laboratory rat handling, surgical technique for induction of neuropathic pain, and behavioral methods.