Project:

Pathophysiology of calcium channels

Mentor (Advisor):

Dr. Norbert Weiss, PhD

Department:

Department of Pathophysiology

Contact information:

, +420739387129

http://www.theweisslab.com

Project Narrative:

Project Narrative: (max. 500 characters including spaces): Neuronal calcium channelopathies are a heterogeneous group of disorders resulting from the dysfunction of calcium channels located in the membranes of all cells and many cellular organelles. There are two types of channelopathies: congenital and acquired. Congenital conditions are genetic in nature and can be inherited or the result of spontaneous mutations. Acquired conditions occur usually later in life and are the result of alteration of ion channels functions caused by aging, drugs, toxins and other cellular environment. The project is directed toward understanding the molecular and physiological factors controling the functioning of neuronal calcium channels in health and disease.

Requirements for student applicants:

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